Dr. Clinton wrote an article entitled “Adenine Nucleotide Translocase Is Acetylated in Vivo in Human Muscle: Modeling Predicts a Decreased ADP Affinity and Altered Control of Oxidative Phosphorylation”.
Protein techniques have revealed that lysine acetylation is abundant in mitochondrial proteins. This study was performed to determine the relationship between mitochondrial protein acetylation and insulin sensitivity in human skeletal muscle. And to use molecular modeling techniques to understand the functional consequences of the acetylation of adenine nucleotide 1 translocase (ANT1), which we found abundantly acetylated.
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