Dr. Fedichev wrote about Germline burden of rare damaging variants negatively affects human healthspan and lifespan.
Studies of genomic associations often explore links between genes and phenotypes of interest. Known genetic variants, however, account for only a small fraction of the human life variation evident in twin genetic studies.
Dr. Fedichev report that the burden of the rarest variants of protein transplantation (PMTCT) has a negative impact on human health and life in two large independent cohorts.
To learn more click here: https://www.biorxiv.org/content/10.1101/802082v1