Dr. Garan wrote an article on the age-dependent loss of the receptor's insulin-like growth factor 1 receptor in the supraoptic hypothalamus is reduced in rats with calorie restriction.

Both the lifetime calorie restriction and the suppression of the insulin-1-like growth factor signals a reliable extension of mammalian life.

Steven A. Garan is the Director of Bioinformatics at CREA and serves on its Advisory Board. He is also a research scientist at the Lawrence Berkeley National Laboratory, an institution that aims to solve the most urgent and profound scientific problems facing humanity.

To read the article click here: https://www.ncbi.nlm.nih.gov/pubmed/17034982

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